Tosoh Bioscience: Size Exclusion Chromatography

Tosoh Bioscience is an acknowledged leader in the field of bioseparations. Established over 22 years ago as TosoHaas, their TSK-GEL & TOYOPEARL chromatographic resins are important components in the analysis, isolation and purification of biomolecules.

Size Exclusion Chromatography

Toyopearl and TSK-GEL polymeric SEC materials are available in a number of pore sizes and particle diameters. With some limited exceptions, and certain applications such as desalting, SEC is not typically used at process scale. Using molecular size as the only separation mechanism, and not adsorption, eliminates the possibility of any binding capacity for the resin. This makes SEC an inefficient technique for manufacturing.However the pore sizes, particle sizes, and physical properties of these beads are important to understand, as they become the base beads for our IEX, HIC, and AFC products.

Toyopearl Resins for SEC

Toyopearl HW-40
Toyopearl HW-50
Toyopearl HW-55
Toyopearl HW-65
Toyopearl HW-75

For further information - download the technical pdf:

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